2x Quadro P5000 with mosaic

I was wondering if anyone has experience / tips on how to set up this wall for generative content? I’m running a test with a GLSL Top and as soon as the op is on it makes everything almost unusable slow (3-4 seconds delay in TD Gui) As I currently understand the two gpu setup with mosaic has some consequences. My question is if it’s possible at all to run GLSL on a configuration like this?
p5000.jpg

GLSL itself shouldn’t be an issue, everything is GLSL underneath. What is the code actually doing? How does it run on a single GPU?