Windows Enterprise / “Pro for Workstations” / IoT enable a feature which allows you to designate a display as “specialized” and remove it from the desktop environment. This seems to be primarily to support HMD hardware but also:
- Specialized “appliance” scenarios where a monitor may be fully dedicated to an app without any interference from the Windows desktop experience over a long period of time (e.g. a dedicated video monitor).
As someone who works primarily in permanent site-specific installations, I would love to keep my main display output(s) out of the windows desktop environment for obvious reasons, and the potential to cut out the complexity of the DWM is enticing as well.
Head-mounted and specialized monitors - Windows drivers | Microsoft Docs